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Can you help me understand this Biology question?

We are regularly bombarded with advertisements for supplements that will help us lose that ugly fat the fast and easy way with no diet or exercise required. Your best friend insists on purchasing every new supplement that hits the market in the hopes of shedding a few pounds. As a scientifically educated person, you know that the Food and Drug Administration does not regulate these supplement companies and that their claims are typically not backed by good scientific evidence. Explain to your roommate some of the risks associated with taking these supplements (based on what you know about cellular respiration and metabolism) and what will work best to lose weight.

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